Frontiers in Immunology

Clinical Trial

Accepted on 31 Jan 2025

Randomised clinical trial in cancer patients shows immune metabolic effects exerted by formulated bioactive phenolic diterpenes with potential clinical benefits

in Nutritional Immunology

Marta Gómez de Cedrón
Juan Moreno-Rubio
Victor de La O Pascual
Beatriz Alvarez
Marta Villarino
María Sereno
César Gómez-Raposo
Silvia Roa
Miriam López Gómez
María Merino-Salvador

Frontiers in Immunology

doi 10.3389/fimmu.2025.1519978

Review

Accepted on 31 Jan 2025

Clinical Evidence of Immunogenicity of CAR-T Cell Therapies and Its Implication in the Clinical Development of CAR-T Drug Products

in Cancer Immunity and Immunotherapy

Hammodah R. Alfar
Cecil Chen
Eric Lachacz
Weifeng Tang
Yuqian Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1512494

General Commentary

Accepted on 31 Jan 2025

Commentary: Sodium levels and immunotherapy efficacy in mRCC patients with bone metastases: sub analysis of the Meet-Uro 15 study

in Cancer Immunity and Immunotherapy

Martina Catalano
Sara Elena Rebuzzi
Giuseppe Fornarini
Giandomenico Roviello

Frontiers in Immunology

doi 10.3389/fimmu.2025.1555559

Original Research

Accepted on 31 Jan 2025

Similarities and differences of a proliferation-inducing ligand expression in lacrimal gland lesions of patients with IgG4-associated ophthalmic diseases and mucosaassociated lymphoid tissue lymphoma

in Cancer Immunity and Immunotherapy

Lvfu He
Lisha Zhan
Yu Yang
Weimin He

Frontiers in Immunology

doi 10.3389/fimmu.2025.1514003

Review

Published on 31 Jan 2025

Multifaceted roles of ninjurin1 in immunity, cell death, and disease

in Molecular Innate Immunity

Lili Zhu
Yunfei Xu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1519519

Technology and Code

Published on 31 Jan 2025

Gene prediction of immune cells association between gut microbiota and colorectal cancer: a Mendelian randomization study

in Microbial Immunology

Yan Zhong
Guanglei Chen
Menglu Chen
Junsong Cui
Qianren Tan
Zhenghua Xiao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1460936

Review

Published on 31 Jan 2025

The role of complement in tumor immune tolerance and drug resistance: a double-edged sword

in Cancer Immunity and Immunotherapy

Ronghui Yang
Di Fu
Aijun Liao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1529184

Editorial

Published on 31 Jan 2025

Editorial: Chrono-immunonutrition in aquaculture towards robust and resilient fish

in Comparative Immunology

Byron Morales-Lange
Maria del Mar Ortega-Villaizan
Sérgio D. C. Rocha
Ruth Montero
Margareth Øverland

Frontiers in Immunology

doi 10.3389/fimmu.2024.1547738

259 views

Original Research

Published on 31 Jan 2025

Structural engineering of stabilized, expanded epitope nanoparticle vaccines for HPV

in Vaccines and Molecular Therapeutics

Michaela Helble
Xizhou Zhu
Pratik S. Bhojnagarwala
Kevin Liaw
Yangcheng Gao
Amber Kim
Kelly Bayruns
Madison E. McCanna
Joyce Park
Kylie M. Konrath

Frontiers in Immunology

doi 10.3389/fimmu.2025.1535261

146 views

Brief Research Report

Published on 31 Jan 2025

CD94-driven in vitro expansion of highly functional adaptive NKG2C+ NKG2A- CD57+ NK cells from CMV+ healthy donors

in Cancer Immunity and Immunotherapy

Chiara Giordano
Simona Carlomagno
Michela Falco
Claudia Cantoni
Massimo Vitale
Ignazio Caruana
Johannes Dirks
Alberto Serio
Letizia Muccio
Giulia Bartalucci

Frontiers in Immunology

doi 10.3389/fimmu.2025.1481745

Case Report

Published on 31 Jan 2025

Case report: Novel multi-exon homozygous deletion of ZBTB24 causes immunodeficiency, centromeric instability, and facial anomalies syndrome 2

in Primary Immunodeficiencies

Yan Long
Chenghan Wang
Jie Xiao
Yunhua Huang
Xiaoting Ling
Chaoyu Huang
Ying Chen
Jiaqi Luo
Rongheng Tang
Faquan Lin

Frontiers in Immunology

doi 10.3389/fimmu.2025.1517417

Mini Review

Published on 31 Jan 2025

Exploring the role of ubiquitination modifications in migraine headaches

in Molecular Innate Immunity

Qian Zhu
Jin Yang
Lei Shi
Jieying Zhang
Peng Zhang
Junlong Li
Xiaoli Song

Frontiers in Immunology

doi 10.3389/fimmu.2025.1534389

Original Research

Published on 31 Jan 2025

Adjuvant-free, self−assembling ferritin nanoparticle vaccine coupled with influenza virus hemagglutinin protein carrying M1 and PADRE epitopes elicits cross-protective immune responses

in Vaccines and Molecular Therapeutics

Yongqiang Zhao
Shuangshuang Guo
Jia Liu
Yating Wang
Bo Wang
Chun Peng
Enqi Du

Frontiers in Immunology

doi 10.3389/fimmu.2025.1519866

146 views

Original Research

Published on 31 Jan 2025

SIRI and SII as potential biomarkers of disease activity and lupus nephritis in systemic lupus erythematosus

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Chi-Hui Yang
Xin-Yi Wang
Yi-Hui Zhang
Ning Ding

Frontiers in Immunology

doi 10.3389/fimmu.2025.1530534

Original Research

Published on 31 Jan 2025

Atractylenolide-I prevents abdominal aortic aneurysm formation through inhibiting inflammation

in Inflammation

Shuxiao Chen
Xiaotian Liu
Xincheng Zhou
Weixiao Lin
Minting Liu
Haoran Ma
Keli Zhong
Qiming Ma
Chengjian Qin

Frontiers in Immunology

doi 10.3389/fimmu.2025.1486072

Original Research

Published on 31 Jan 2025

Biomarker combinations from different modalities predict early disability accumulation in multiple sclerosis

in Multiple Sclerosis and Neuroimmunology

Vinzenz Fleischer
Tobias Brummer
Muthuraman Muthuraman
Falk Steffen
Milena Heldt
Maria Protopapa
Muriel Schraad
Gabriel Gonzalez-Escamilla
Sergiu Groppa
Stefan Bittner

Frontiers in Immunology

doi 10.3389/fimmu.2025.1532660

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Articles

Randomised clinical trial in cancer patients shows immune metabolic effects exerted by formulated bioactive phenolic diterpenes with potential clinical benefits

Clinical Evidence of Immunogenicity of CAR-T Cell Therapies and Its Implication in the Clinical Development of CAR-T Drug Products

Commentary: Sodium levels and immunotherapy efficacy in mRCC patients with bone metastases: sub analysis of the Meet-Uro 15 study

Similarities and differences of a proliferation-inducing ligand expression in lacrimal gland lesions of patients with IgG4-associated ophthalmic diseases and mucosaassociated lymphoid tissue lymphoma

Multifaceted roles of ninjurin1 in immunity, cell death, and disease

Gene prediction of immune cells association between gut microbiota and colorectal cancer: a Mendelian randomization study

The role of complement in tumor immune tolerance and drug resistance: a double-edged sword

Editorial: Chrono-immunonutrition in aquaculture towards robust and resilient fish

Structural engineering of stabilized, expanded epitope nanoparticle vaccines for HPV

CD94-driven in vitro expansion of highly functional adaptive NKG2C+ NKG2A- CD57+ NK cells from CMV+ healthy donors

Case report: Novel multi-exon homozygous deletion of ZBTB24 causes immunodeficiency, centromeric instability, and facial anomalies syndrome 2

Exploring the role of ubiquitination modifications in migraine headaches

Adjuvant-free, self−assembling ferritin nanoparticle vaccine coupled with influenza virus hemagglutinin protein carrying M1 and PADRE epitopes elicits cross-protective immune responses

SIRI and SII as potential biomarkers of disease activity and lupus nephritis in systemic lupus erythematosus

Atractylenolide-I prevents abdominal aortic aneurysm formation through inhibiting inflammation

Biomarker combinations from different modalities predict early disability accumulation in multiple sclerosis