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EDITORIAL article
Front. Immunol.
Sec. Molecular Innate Immunity
Volume 16 - 2025 | doi: 10.3389/fimmu.2025.1608192
This article is part of the Research TopicMolecular Innate Immunity in Aquatic Animals and Their Response to Epidemic DiseasesView all 7 articles
Editorial: Molecular Innate Immunity in Aquatic Animals and Their Response to Epidemic Diseases
Provisionally accepted- 1Hainan University, Haikou, Hainan Province, China
- 2The Ohio State University, Columbus, Ohio, United States
- 3Dalian Ocean University, Dalian, Liaoning, China
- 4Fujian Agriculture and Forestry University, Fuzhou, China
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In addition, another significant study examined the effects of mycotoxins on the innate immune system of aquatic animals. Zheng et al. explored the immunotoxicity of ochratoxin A (OTA) in zebrafish, focusing on its impact on innate immunity. The study found that OTA exposure inhibited embryonic development, reduced neutrophil and macrophage numbers, and impaired immune cell migration during fin regeneration.Transcriptome analysis showed that OTA upregulated the apoptosis pathway mediated by anxa1a and anxa1d in neutrophils. Moreover, aesculetin was shown to mitigate the immunotoxic effects of OTA, indicating its potential as a therapeutic agent. These studies have not only provided new theoretical foundations for aquatic animal immunology but also offered valuable guidance for aquaculture practices. The integration of environmental sensors with gene-editing technologies holds the potential to achieve a dual breakthrough in dynamic dissolved oxygen control and the breeding of disease-resistant varieties, promoting the development of the aquaculture industry toward greater intelligence and sustainability.
Keywords: innate immunity, aquatic animals, epidemic diseases, Aeromonas hydrophila, Antibacterial immune
Received: 08 Apr 2025; Accepted: 14 Apr 2025.
Copyright: © 2025 Lu, Liao, Sun, Yang and Deng. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Hengwei Deng, Hainan University, Haikou, 570228, Hainan Province, China
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