SYSTEMATIC REVIEW article

Front. Immunol.

Sec. Cancer Immunity and Immunotherapy

Volume 16 - 2025 | doi: 10.3389/fimmu.2025.1587867

This article is part of the Research TopicCommunity Series in The Immunosuppressive Tumor Microenvironment and Strategies to Revert its Immune Regulatory Milieu for Cancer Immunotherapy: Volume IIView all 5 articles

Research Trends on Lactate in Cancer ： A Bibliometric Analysis and Comprehensive Review (2015-2024)

Provisionally accepted
Sinong LiSinong Li1Ziyi YangZiyi Yang1Mutian LvMutian Lv2Lin ZongLin Zong3Yihan XieYihan Xie1Zoujuan CaiZoujuan Cai1Ying ZhangYing Zhang1Zhongqing WangZhongqing Wang4Zhe LiuZhe Liu5Liang SangLiang Sang1*
  • 1Department of Ultrasound, The First Hospital of China Medical University, Shenyang, China
  • 2Department of Nuclear Medicine, The First Affiliated Hospital of China Medical University, Shengyang, China
  • 3Department of Neurosurgery, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning Province, China
  • 4Department of Information Center, The First Hospital of China Medical University, Shenyang, China
  • 5Department of Pancreatic-Biliary Surgery, The First Hospital of China Medical University, Shenyang, China

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Objective: A bibliometric approach was employed to systematically analyze the trends and potential future developments in lactic acid-related cancer research over the past 10 years.Method: We conducted a bibliometric analysis of literature on lactic acid in cancer research from 2015 to 2024, using data collected from the Web of Science database. A bibliometric analysis was conducted to identify general research directions and trends in current publications, as well as to determine the most prolific and influential authors, institutions, countries, and keywords in lactate and cancer research. The data were collected and analyzed using

Keywords: Lactic Acid, Cancer, bibliometric analysis, VOSviewer, Citespace

Received: 05 Mar 2025; Accepted: 15 Apr 2025.

Copyright: © 2025 Li, Yang, Lv, Zong, Xie, Cai, Zhang, Wang, Liu and Sang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Liang Sang, Department of Ultrasound, The First Hospital of China Medical University, Shenyang, China

Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

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