AUTHOR=Xie Dong , Liu Yang , Xu Fangbiao , Dang Zhibo , Li Mengge , Zhang Qinsheng , Dang Zhongqin TITLE=Immune microenvironment and immunotherapy in hepatocellular carcinoma: mechanisms and advances JOURNAL=Frontiers in Immunology VOLUME=16 YEAR=2025 URL=https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2025.1581098 DOI=10.3389/fimmu.2025.1581098 ISSN=1664-3224