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CASE REPORT article
Front. Immunol.
Sec. B Cell Biology
Volume 16 - 2025 | doi: 10.3389/fimmu.2025.1564242
Efficacy of Telitacicept in Treating IgA Vasculitis Nephritis: A Two-Case Report
Provisionally accepted- 1Changhai Hospital, Second Military Medical University, Shanghai, China
- 2Medical School of Chinese People's Liberation Army (PLA), beijing, China
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Telitacicept, a B lymphocyte stimulator/A proliferation-inducing ligand dual-target fusion protein, mainly used for IgA nephropathy and systemic lupus erythematosus. We present two cases where adult patients with IgA vasculitis (IgAV) nephritis were successfully treated with Telitacicept, experienced no adverse reactions during the follow-up. Therefore, Telitacicept represents a promising additional treatment option for patients suffering from IgA vasculitis (IgAV).
Keywords: Telitacicept, IgA vasculitis, April, BAFF, Henoch-Schönlein purpura (HSP)
Received: 21 Jan 2025; Accepted: 02 Apr 2025.
Copyright: © 2025 Li, Hu, Kong, bian, Xu, Guo and Mei. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Xiaobin Mei, Changhai Hospital, Second Military Medical University, Shanghai, China
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.