AUTHOR=Rubin Tamar , Bernier Stéphane , Hoon Lim Lily Siok , Salman Michael S. , Leung Edward , Mhanni Aziz , Marles Sandra , Greenberg Cheryl , Perez Anna , Sun Yichun , Angers Isabelle , Vinh Donald C. , Roussel Lucie 

TITLE=Two rare mutations in homozygosity synergize to silence TREX1 in Aicardi-Goutières syndrome

JOURNAL=Frontiers in Immunology

VOLUME=16

YEAR=2025

URL=https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2025.1557632

DOI=10.3389/fimmu.2025.1557632

ISSN=1664-3224