AUTHOR=Guo Zhaomeng , Li Kang , Ren Xiaotong , Wang Xijia , Yang Dunhui , Ma Shibo , Zeng Xianhai , Zhang Peng TITLE=The role of the tumor microenvironment in HNSCC resistance and targeted therapy JOURNAL=Frontiers in Immunology VOLUME=Volume 16 - 2025 YEAR=2025 URL=https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2025.1554835 DOI=10.3389/fimmu.2025.1554835 ISSN=1664-3224