95% of researchers rate our articles as excellent or good
Learn more about the work of our research integrity team to safeguard the quality of each article we publish.
Find out more
CASE REPORT article
Front. Immunol.
Sec. Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders
Volume 16 - 2025 | doi: 10.3389/fimmu.2025.1553793
Ustekinumab is effective in the treatment of linear psoriasis: a case report and literature review
Provisionally accepted- The First hospital of Hebei Medical University, Shijiazhuang, Hebei Province, China
Linear psoriasis is a rare type of psoriasis that usually presents as scaly papules and plaques unilaterally distributed along the Blaschko line. Currently, the pathogenesis of linear psoriasis is not fully understood, and genetic mosaicism may be one of the explanations. As linear psoriasis is less responsive to treatment than psoriasis vulgaris, there is no consensus on treatment guidelines specifically for this disease, and the efficacy of ustekinumab in treating this category has not been reported. In this article, we present a case of effective treatment of linear psoriasis with ustekinumab and review the relevant literatures, hoping to help clinicians better understand and treat this disease.
Keywords: Psoriasis, Blaschko line, Ustekinumab, Inducement, Treatment
Received: 02 Jan 2025; Accepted: 28 Mar 2025.
Copyright: © 2025 Qi, Zhu, Feng, Liu and Zhang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Guoqiang Zhang, The First hospital of Hebei Medical University, Shijiazhuang, 050000, Hebei Province, China
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.