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CASE REPORT article
Front. Immunol.
Sec. Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders
Volume 16 - 2025 | doi: 10.3389/fimmu.2025.1551094
Case report: A case of membranous nephropathy associated with primary Sjögren's syndrome treated with telitacicept
Provisionally accepted- 1 Yuyao People's Hospital, Yuyao, Zhejiang, China
- 2 Ningbo Second Hospital, Ningbo, Zhejiang Province, China
Primary Sjögren’s syndrome (pSS) is an autoimmune disease that often affects the exocrine glands. However, pSS can also affect the kidneys, most commonly involving the kidney interstitium. Recent studies have demonstrated that some membranous nephropathy (MN) cases are associated with Sjögren’s syndrome. However, unified recommendations for selecting immunosuppressive agents for treating MN associated with pSS are currently lacking. In the case reported herein, a patient with MN associated with pSS experienced improvement following methylprednisolone and telitacicept treatment.
Keywords: primary Sjögren's syndrome, Membranous nephropathy, Telitacicept, B cells, Urine protein, albumin
Received: 24 Dec 2024; Accepted: 24 Mar 2025.
Copyright: © 2025 Chen, Zhou, Shen, Pang and Chu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Hanqing Chu, Yuyao People's Hospital, Yuyao, Zhejiang, China
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