Skip to main content

ORIGINAL RESEARCH article

Front. Immunol.

Sec. Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Volume 16 - 2025 | doi: 10.3389/fimmu.2025.1547763

Global, Regional, and National Burden and Trends of Rheumatoid Arthritis among the Elderly Population: An Analysis Based on the 2021 Global Burden of Disease Study

Provisionally accepted
Lu Wei Lu Wei 1Xiang Chen Xiang Chen 2Meng meng Liu Meng meng Liu 3*
  • 1 Department of Trauma Center, Liuzhou Workers Hospital, Liuzhou, Guangxi Zhuang Region, China
  • 2 Department of Bone and Joint Surgery, First Affiliated Hospital, Guangxi Medical University, Nanning, China
  • 3 School of Physical Education And Health, Guangxi Medical University, Nanning, Guangxi Zhuang Region, China

The final, formatted version of the article will be published soon.

    Rheumatoid arthritis (RA) is an autoimmune and inflammatory disease. In elderly patients, the disease progresses more rapidly, involves more complications, and places a greater burden on health. Currently, there is a lack of studies investigating the disease burden of RA in the elderly population.We analyzed data on elderly rheumatoid arthritis from the Global Burden of Disease (GBD) database for 1990-2021, focusing on three main indicators: prevalence, incidence, and Disability-Adjusted Life Years (DALYs). Percentage change and the estimated annual percentage change (EAPC) were used to evaluate the trends in the disease burden.

    Keywords: Rheumatoid arthritis, Elderly, disease burden, Prevalence, Incidence, DALYs

    Received: 18 Dec 2024; Accepted: 31 Mar 2025.

    Copyright: © 2025 Wei, Chen and Liu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Meng meng Liu, School of Physical Education And Health, Guangxi Medical University, Nanning, 530021, Guangxi Zhuang Region, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

    Research integrity at Frontiers

    Man ultramarathon runner in the mountains he trains at sunset

    95% of researchers rate our articles as excellent or good

    Learn more about the work of our research integrity team to safeguard the quality of each article we publish.


    Find out more