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REVIEW article
Front. Immunol.
Sec. Immunological Tolerance and Regulation
Volume 16 - 2025 | doi: 10.3389/fimmu.2025.1546704
Trends and hotspots on hymenoptera venom immunotherapy: A bibliometric and visualized analysis of research from 2014 to 2024
Provisionally accepted- Yongchuan Hospital of Chongqing Medical University, Chongqing, China
Objective : Recently, the application of hymenoptera venom immunotherapy(VIT) has been extensively studied in the medical community. Nevertheless, there are still very few bibliometric analyses devoted to this field. Therefore, this study aims to provide a comprehensive overview of the development of research in the past 11 years and clarify future research directions and trends.Methods : From 2014 to 2024, articles related to "hymenoptera venom immunotherapy "and "Allergy" were from the core collection of Web of Science.This visual analysis included examining annual productivity,cooperation between countries and institutions, co-cited references, author and journal cooperation networks, keyword co -occurrence, and their respective clustering and trends.Results : A total of 332 articles on the allergy caused by hymenoptera VIT were included in this study. Germany, Azienda Ospedaliera Universitaria Integrata Verona and Golden, David B K are the most productive countries and institutions respectively. Analysis of the top 10 literatures with co-citation frequency found that 4 were expert consensus and guidelines, 4 were single-center (or multi-center ), open, randomized controlled trials, and 2 were systematic reviews. Keyword cluster analysis showed that wasps were identified as the primary focus of hymenoptera VIT in the past, and mastocytosis and hymenopteran venom allergy were the current research hotspots.Conclusion :Recent studies on hymenoptera VIT have shown that today 's VIT increasingly emphasizes individualized and refined treatment. However, there is a lack of evidence of multicenter randomized controlled trials ( RCTs ) in this field. To solve this problem, further research is needed.
Keywords: bibliometric analysis, Venom immunotherapy, Citespace, allergy, Hymenoptera
Received: 17 Dec 2024; Accepted: 03 Apr 2025.
Copyright: © 2025 Luo, Guan and Yu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Yichuan Yu, Yongchuan Hospital of Chongqing Medical University, Chongqing, China
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.