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REVIEW article
Front. Immunol.
Sec. Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders
Volume 16 - 2025 | doi: 10.3389/fimmu.2025.1545760
IL-7 in Autoimmune Diseases: Mechanisms and Therapeutic Potential
Provisionally accepted- Southwest Medical University, Luzhou, China
This review focuses on the role of Interleukin-7 (IL-7) in autoimmune diseases.Interleukin-7 (IL-7) is a pleiotropic cytokine that plays a crucial role in the development, homeostasis, and function of the immune system. In recent years, accumulating evidence has demonstrated that IL-7 is involved in the pathogenesis of various autoimmune diseases including rheumatoid arthritis, systemic lupus erythematosus, and multiple sclerosis. This review aims to summarize the current understanding of the role of IL-7 in autoimmune diseases, focusing on its mechanisms of action, implications for disease progression, and potential therapeutic applications.
Keywords: IL-7, Autoimmune Diseases, cytokine, T cells, B cells, therapeutic targets
Received: 15 Dec 2024; Accepted: 14 Mar 2025.
Copyright: © 2025 Zeng, Mao, Lei and He. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Yuanmin He, Southwest Medical University, Luzhou, China
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