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CASE REPORT article

Front. Immunol.

Sec. Primary Immunodeficiencies

Volume 16 - 2025 | doi: 10.3389/fimmu.2025.1545165

This article is part of the Research Topic Immune Correlates of Protection: Insight into Microbial co-infection with Special Emphasis on Influenza-Streptococcus pneumoniae Superinfection View all 5 articles

Case Report: Infection with Streptococcus constellatus Manifesting as Gelatinous Pleural Effusion in an HIV-Positive Patient

Provisionally accepted
Zhongxia Yang Zhongxia Yang *Wanyuan Xiong Wanyuan Xiong Zibing Qian Zibing Qian Xiaorong Mao Xiaorong Mao
  • First Hospital of Lanzhou University, Lanzhou, China

The final, formatted version of the article will be published soon.

    Streptococcus constellatus, recognized as a commensal bacterium, has the potential to induce severe infections in patients with immunodeficiency. Here, we reported a rare case of Streptococcus constellatus infection that manifested as gelatinous pleural effusion in a patient with HIV. Although the effusion was gelatinous and partially encapsulated, it was completely resolved with timely administration of antibiotics, thereby eliminating the necessity for thoracic drainage, urokinase injection, or surgical intervention.

    Keywords: Streptococcus constellatus, gelatinous, Pleural Effusion, HIV, Infection

    Received: 14 Dec 2024; Accepted: 26 Feb 2025.

    Copyright: © 2025 Yang, Xiong, Qian and Mao. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Zhongxia Yang, First Hospital of Lanzhou University, Lanzhou, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

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