AUTHOR=Guo Zhi-Xun , Ma Jia-Li , Zhang Jin-Qiu , Yan Ling-Ling , Zhou Ying , Mao Xin-li , Li Shao-Wei , Zhou Xian-Bin TITLE=Metabolic reprogramming and immunological changes in the microenvironment of esophageal cancer: future directions and prospects JOURNAL=Frontiers in Immunology VOLUME=16 YEAR=2025 URL=https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2025.1524801 DOI=10.3389/fimmu.2025.1524801 ISSN=1664-3224