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CASE REPORT article
Front. Immunol.
Sec. Microbial Immunology
Volume 16 - 2025 | doi: 10.3389/fimmu.2025.1521161
This article is part of the Research Topic Host and Microbe Immunometabolic Chat: A New Era of Organismal Communication View all 4 articles
A rare case of community-acquired Roseomonas mucosa sepsis that presented with persistently normal host-response biomarkers
Provisionally accepted- Chengdu Fifth People's Hospital, Chengdu, China
Community-acquired Roseomonas mucosa sepsis can lead to significant morbidity and mortality if not diagnosed promptly. We report a case of a 59-year-old woman with community-acquired Roseomonas mucosa sepsis who presented with persistent fever progressing to septic shock, despite repeatedly negative host-response biomarker results. Initial metagenomic analysis of peripheral blood suggested Pseudomonas aeruginosa infection. However, a peripheral blood culture identified Roseomonas mucosa as the causative pathogen. She was cured after switching to meropenem according to blood cultures and antimicrobial susceptibility testing.
Keywords: Roseomonas mucosa, Sepsis, Inflammatory biomarkers, metagenomic next-generation sequencing, Blood culture
Received: 01 Nov 2024; Accepted: 25 Mar 2025.
Copyright: © 2025 Xu, Li and Huang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Xiaomei Xu, Chengdu Fifth People's Hospital, Chengdu, China
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