AUTHOR=Li Baohua , Sha Zhou , Mou Li , Zhang Feng , Jia Lifeng , Zhu Yan , Guo Yan , Deng Guohong , Wu Haibo , Wei Hong , Wu Yuzhang , Ye Lilin , Liu Changjiang , Li Jian , Zhang Yanyan TITLE=Commensal bacteria education history calibrates the naivety and activation threshold of adaptive antiviral immune system JOURNAL=Frontiers in Immunology VOLUME=16 YEAR=2025 URL=https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2025.1519023 DOI=10.3389/fimmu.2025.1519023 ISSN=1664-3224