AUTHOR=Wang Qin , Zhu Xinyi , Li Jing , Xu Sanjia , Wang Ali , Zhang Xinwen , Wang Xingxing , Cai Xiaopeng , Xing Haimei , Liu Ye , Liu Xuesong , Wang Zhiwei , Wang Lai , Yuan Xi 

TITLE=HPK1 kinase inhibitor: a sufficient approach to target HPK1 to modulate T cell activation in cancer immunotherapy compared with degraders

JOURNAL=Frontiers in Immunology

VOLUME=16

YEAR=2025

URL=https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2025.1449106

DOI=10.3389/fimmu.2025.1449106

ISSN=1664-3224