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MINI REVIEW article

Front. Immunol.
Sec. Cancer Immunity and Immunotherapy
Volume 15 - 2024 | doi: 10.3389/fimmu.2024.1537013
This article is part of the Research Topic Harnessing Molecular Insights for Enhanced Drug Sensitivity and Immunotherapy in Cancer View all 10 articles

Advancements in Targeted and Immunotherapy Strategies for Glioma: Toward Precision Treatment

Provisionally accepted
Gong Guangyuan Gong Guangyuan 1Lang Jiang Lang Jiang 1*Jing Zhou Jing Zhou 2*Yuanchao Su Yuanchao Su 3*
  • 1 Department of Intensive Care Medicine, Jiangsu Provincial People's Hospital Chongqing Hospital (Qijiang District People's Hospital), Chongqing 401420, China, Chongqing, China
  • 2 Department of Thoracic Surgery, Jiangsu Provincial People's Hospital Chongqing Hospital (Qijiang District People's Hospital), Chongqing 401420, China, Chongqing, China
  • 3 Department of Emergency Medicine, Jiangsu Provincial People's Hospital Chongqing Hospital (Qijiang District People's Hospital), Chongqing 401420, China, Chongqing, China

The final, formatted version of the article will be published soon.

    In recent years, significant breakthroughs have been made in cancer therapy, particularly with the development of molecular targeted therapies and immunotherapies, owing to advances in tumor molecular biology and molecular immunology. High-grade gliomas (HGGs), characterized by their high malignancy, remain challenging to treat despite standard treatment regimens, including surgery, radiotherapy, chemotherapy, and tumor treating fields (TTF). These therapies provide limited efficacy, highlighting the need for novel treatment strategies. Molecular targeted therapies and immunotherapy have emerged as promising avenues for improving treatment outcomes in high-grade gliomas. This review explores the current status and recent advancements in targeted and immunotherapeutic approaches for high-grade gliomas.

    Keywords: high-grade glioma, Immunotherapy, targeted therapy, Molecular Biology, Treatment

    Received: 29 Nov 2024; Accepted: 23 Dec 2024.

    Copyright: © 2024 Guangyuan, Jiang, Zhou and Su. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Lang Jiang, Department of Intensive Care Medicine, Jiangsu Provincial People's Hospital Chongqing Hospital (Qijiang District People's Hospital), Chongqing 401420, China, Chongqing, China
    Jing Zhou, Department of Thoracic Surgery, Jiangsu Provincial People's Hospital Chongqing Hospital (Qijiang District People's Hospital), Chongqing 401420, China, Chongqing, China
    Yuanchao Su, Department of Emergency Medicine, Jiangsu Provincial People's Hospital Chongqing Hospital (Qijiang District People's Hospital), Chongqing 401420, China, Chongqing, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.