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CASE REPORT article

Front. Immunol.
Sec. Multiple Sclerosis and Neuroimmunology
Volume 15 - 2024 | doi: 10.3389/fimmu.2024.1517943
This article is part of the Research Topic Monoclonal antibodies in treating multiple sclerosis (MS), and related diseases. View all 8 articles

Severe Guillain-Barré Syndrome with Concurrent Optic Neuritis in a Pediatric Patient: A Case Report

Provisionally accepted
Xue 辛 Xue 辛 Yingcun Bao Yingcun Bao *Yakun Yu Yakun Yu *Qun Li Qun Li *Mei Liu Mei Liu *Xiaoling Li Xiaoling Li *
  • Lanzhou University Second Hospital, Lanzhou, Gansu Province, China

The final, formatted version of the article will be published soon.

    This case report presents the first known pediatric case in China of GBS complicated by bilateral optic neuritis, triggered by an upper respiratory infection. The rarity of this combination, particularly in a child, underscores the complexity of diagnosis and treatment, highlighting the need for timely intervention to prevent severe sequelae. This report aims to contribute valuable insights into the pathophysiology, clinical management, and treatment outcomes of GBS/ON, with a particular focus on the role of rituximab.

    Keywords: Guillain-Barré syndrome, Optic Neuritis, pediatric neurology, Immunotherapy, rituximab, case report

    Received: 27 Oct 2024; Accepted: 19 Dec 2024.

    Copyright: © 2024 辛, Bao, Yu, Li, Liu and Li. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Yingcun Bao, Lanzhou University Second Hospital, Lanzhou, 730030, Gansu Province, China
    Yakun Yu, Lanzhou University Second Hospital, Lanzhou, 730030, Gansu Province, China
    Qun Li, Lanzhou University Second Hospital, Lanzhou, 730030, Gansu Province, China
    Mei Liu, Lanzhou University Second Hospital, Lanzhou, 730030, Gansu Province, China
    Xiaoling Li, Lanzhou University Second Hospital, Lanzhou, 730030, Gansu Province, China

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