AUTHOR=Lian Heping , Zhang Jiakui , Hou Shuna , Ma Shuang , Yu Jiachen , Zhao Wei , Zhao Duoyi , Zhang Zhiyu TITLE=Immunotherapy of osteosarcoma based on immune microenvironment modulation JOURNAL=Frontiers in Immunology VOLUME=15 YEAR=2025 URL=https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2024.1498060 DOI=10.3389/fimmu.2024.1498060 ISSN=1664-3224