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CASE REPORT article
Front. Immunol.
Sec. Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders
Volume 15 - 2024 |
doi: 10.3389/fimmu.2024.1483993
Successful Remission with Upadacitinib in a young Patient with Anti-TNF-Refractory Intestinal Behçet's disease
Provisionally accepted- 1 Xi'an Jiaotong University, Xi'an, China
- 2 Air Force Medical University, Xi'an, Shaanxi Province, China
The limited therapeutic options and inconsistent treatment efficacy of Intestinal Behçet's disease complicate its management, with the absence of standardized guidelines further exacerbating the challenges faced by clinicians.Case Presentation: In this case report, we present a patient with refractory intestinal Behçet's disease who experienced treatment failure with prior biologic agents. This case sheds light on managing this complex scenario with Janus kinase (JAK) inhibitors, the patient achieved mucosal healing after switching to Upadacitinib.This case underscores the potential of Upadacitinib as an effective alternative for managing difficult cases of intestinal Behçet's disease.
Keywords: Intestinal Behçet's disease, Upadacitinib, case report, mucosal healing, Anti-TNF-Refractory
Received: 21 Aug 2024; Accepted: 18 Oct 2024.
Copyright: © 2024 Sha, Xu, Wang, Qiao, Shi, Jiang, Xiaojing and Liu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Bin Xu, Air Force Medical University, Xi'an, 710032, Shaanxi Province, China
Chenyang Qiao, Xi'an Jiaotong University, Xi'an, 710049, China
Jiong Jiang, Xi'an Jiaotong University, Xi'an, 710049, China
Xin Liu, Xi'an Jiaotong University, Xi'an, 710049, China
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