AUTHOR=Gao Yingna , Shi Xiaoqiong , He Jianqiao , Yao Hui , Yu Guoning , Zhao Lin , Ma Yi , Zheng Hongliang , Zhu Minhui , Zhang Caiyun TITLE=Immunotherapy combined with chemotherapy without locoregional radiotherapy in de novo metastatic nasopharyngeal carcinoma: two case reports and a literature review JOURNAL=Frontiers in Immunology VOLUME=15 YEAR=2025 URL=https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2024.1467355 DOI=10.3389/fimmu.2024.1467355 ISSN=1664-3224