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CASE REPORT article
Front. Immunol.
Sec. Multiple Sclerosis and Neuroimmunology
Volume 15 - 2024 |
doi: 10.3389/fimmu.2024.1459119
Refractory Focal Motor Seizure Associated with Cerebrospinal Fluid Neurochondrin Antibody
Provisionally accepted- University of Texas Medical Branch at Galveston, Galveston, Texas, United States
The Neurochondrin-associated neurological disorder is rare and its principal clinical manifestations observed so far are cerebellar ataxia, rhombencephalitis, and hyperkinetic movements such as chorea. Neurochondrin antibody-associated Autoimmune Epilepsy (AE) has not been previously reported in the literature. This is the first reported case of refractory autoimmune epilepsy with positive CSF anti-neurochondrin antibody. This study reveals an under-recognized role of neurochondrin antibody in epilepsy.
Keywords: Xiangping Li: Conceptualization, supervision, Writing -original draft, Writing -review & editing. Peter R Wang: Writingoriginal draft. Rowaid Ahmad: Writing -original draft. Todd Masel: Conceptualization, Writing -review & editing. Yumeng Huang: Writing -original draft Autoimmune epilepsy, Neurochondrin antibody, norbin, Autoimmune cerebellar ataxia
Received: 05 Jul 2024; Accepted: 26 Aug 2024.
Copyright: © 2024 Ahmad, Huang, Wang, Masel and Li. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Xiangping Li, University of Texas Medical Branch at Galveston, Galveston, 77555, Texas, United States
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