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SYSTEMATIC REVIEW article

Front. Immunol.
Sec. Cancer Immunity and Immunotherapy
Volume 15 - 2024 | doi: 10.3389/fimmu.2024.1454393
This article is part of the Research Topic Cancer Biomarkers: Molecular Insights into Diagnosis, Prognosis, and Risk Prediction View all 6 articles

Association between glucose to lymphocyte ratio and prognosis in patients with solid tumors

Provisionally accepted
Rongqiang Liu Rongqiang Liu 1*Yankun Shen Yankun Shen 1Jiahui Cui Jiahui Cui 2Wangbin Ma Wangbin Ma 1Jianguo Wang Jianguo Wang 1Chen Chen Chen Chen 1Weixing Wang Weixing Wang 1
  • 1 Department of Hepatobilliary Surgery, Renmin Hospital of Wuhan University, Wuhan, China
  • 2 Department of Anesthesiology, Renmin Hospital of Wuhan University, Wuhan, Hebei Province, China

The final, formatted version of the article will be published soon.

    Background: Glucose-to-lymphocyte ratio (GLR) plays an important role in the prognosis of various tumors. The aim of this study was to comprehensively evaluate the prognostic value of GLR in solid tumors through the meta-analysis.Methods: A comprehensive search of eligible studies was performed by scrutinizing the Pubmed, Embase and Web of science databases until May 30, 2024. The pooled hazard ratios (HRs) with 95% confidence intervals (CIs) were calculated to evaluate overall survival (OS), disease-free survival (DFS) and recurrence free survival (RFS).Results: A total of 22 studies from 14 articles involving 9472 patients were included in the study. The pooled analysis showed that cancer patients with high GLR was significantly associated with unfavorable OS

    Keywords: glucose-to-lymphocyte ratio, tumor, prognosis, Meta-analysis, Survival

    Received: 03 Sep 2024; Accepted: 22 Nov 2024.

    Copyright: © 2024 Liu, Shen, Cui, Ma, Wang, Chen and Wang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Rongqiang Liu, Department of Hepatobilliary Surgery, Renmin Hospital of Wuhan University, Wuhan, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.