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SYSTEMATIC REVIEW article

Front. Immunol.
Sec. Cancer Immunity and Immunotherapy
Volume 15 - 2024 | doi: 10.3389/fimmu.2024.1444305

Analyzing Research Trends in Glioblastoma Metabolism: A Bibliometric Review

Provisionally accepted
Jiaxin Dai Jiaxin Dai 1,2Siyun Song Siyun Song 1Pengyu Chen Pengyu Chen 1,2Qixuan Huang Qixuan Huang 3,4Hubin Duan Hubin Duan 1,2*
  • 1 First Hospital of Shanxi Medical University, Taiyuan, Shaanxi, China
  • 2 Department of Neurosurgery, First Hospital of Shanxi Medical University, Taiyuan, Shanxi Province, China
  • 3 Department of Gastrointestinal Surgery, Harbin Medical University Cancer Hospital, Harbin, Heilongjiang Province, China
  • 4 Harbin Medical University, Harbin, Heilongjiang, China

The final, formatted version of the article will be published soon.

    Background: A bibliometric and visual analysis of articles related to glioblastoma metabolism was conducted to reveal the dynamics of scientific development and to assist researchers in gaining a global perspective when exploring hotspots and trends.The Web of Science Core Collection (WoSCC) was employed to search, screen, and download articles about glioblastoma metabolism published between 2014 and 2024. The relevant literature was analyzed using CiteSpace, VOSviewer and Microsoft Excel.Results: A total of 729 articles were included for bibliometric analysis between 2014 and 2024, and the number of articles published each year showed an overall increasing trend, except for a decrease in the number of articles published in 2018 compared to 2017. Collaboration network analysis showed that the United States, Germany and China are influential countries in this field, with a high number of articles published, citations and collaborations with other countries. The journal with the largest number of published articles is the International Journal of Molecular Sciences. Mischel PS is the most prolific author with 14 articles, and Guo DL received the most citations with 104 citations. Keyword analysis of the literature showed that the "Warburg effect" achieved the highest burst intensity, and "central nervous system", "classification" and "fatty acids" showed stronger citation bursts in 2024, indicating that they are still popular topics so far.This article elucidates the research trends and focal points in the field of glioblastoma metabolism, furnishes invaluable insights into the historical and contemporary status of this field, and offers guidance for future research. Further research into glioblastoma metabolism will undoubtedly yield new insights that will inform the diagnosis and treatment of this disease.

    Keywords: Glioblastoma, Metabolize, metabolic reprogramming, Tumor Microenvironment, bibliometric analysis, hotspots

    Received: 12 Jun 2024; Accepted: 01 Oct 2024.

    Copyright: © 2024 Dai, Song, Chen, Huang and Duan. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Hubin Duan, First Hospital of Shanxi Medical University, Taiyuan, 030001, Shaanxi, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.