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CASE REPORT article

Front. Immunol.
Sec. Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders
Volume 15 - 2024 | doi: 10.3389/fimmu.2024.1435141
This article is part of the Research Topic Case Reports in Autoimmune and Autoinflammatory Disorders View all 39 articles

Intralesional Secukinumab injection for pediatric nail psoriasis: Does it have to be a positive outcome?

Provisionally accepted
Xuesong Wang Xuesong Wang 1,2Yonghu Sun Yonghu Sun 1Weixing Xie Weixing Xie 1Hong Liu Hong Liu 1Guoyan Liu Guoyan Liu 1*
  • 1 Shandong Provincial Hospital of Dermatology, Jinan, China
  • 2 Shandong, Jinan, China

The final, formatted version of the article will be published soon.

    Recent studies have shown that local injection of sSecukinumab can achieve positive therapeutic effects when applied in the treatment of nail psoriasis. At present, there have been no other studies on the use of biological agents in the treatment of pediatric nail psoriasis. Three children were included in the study to evaluate the efficacy and safety of periungual injection and long-term injection of sSecukinumab in the treatment of nail psoriasis in children. It was found that local injection did not achieve a remarkablesignificant therapeutic effect. The nail lesions were improved continuously by subcutaneous injection once a month.

    Keywords: Intralesional injection, secukinumab, Nail psoriasis, pediatric, Psoriasis

    Received: 19 May 2024; Accepted: 12 Sep 2024.

    Copyright: © 2024 Wang, Sun, Xie, Liu and Liu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Guoyan Liu, Shandong Provincial Hospital of Dermatology, Jinan, China

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