This article is a correction to:
Impact of ATP-citrate lyase catalytic activity and serine 455 phosphorylation on histone acetylation and inflammatory responses in human monocytic THP-1 cells
Monica Dominguez
Verena Truemper
Ana Carolina Mota
Bernhard Brüne
Dmitry Namgaladze- 1Institute of Biochemistry I, Faculty of Medicine, Goethe-University Frankfurt, Frankfurt, Germany
- 2Fraunhofer Institute for Translational Medicine and Pharmacology (ITMP), Frankfurt, Germany
- 3German Cancer Consortium (DKTK), Partner Site Frankfurt, Frankfurt, Germany
- 4Frankfurt Cancer Institute, Goethe-University Frankfurt, Frankfurt, Germany
By Dominguez M, Truemper V, Mota AC, Brüne B, Namgaladze D. Front Immunol. 2022 Nov 10;13:906127. doi: .10.3389/fimmu.2022.906127
In the published article, there was an error in Figure 3 as published. The western blot images of pACLY/ACLY (Figure 3A) were also mistakenly inserted in Figure 3B in place of pPRAS40/PRAS40 images. The corrected Figure 3 and its caption appear below.
Figure 3
Figure 3 Effects of Akt and PKA inhibition on ACLY phosphorylation, LPS-induced pro-inflammatory cytokine production and basal histone acetylation in THP-1 cells. (A) Western blot analysis of ACLY phosphorylation in ACLY WT cells upon treatment with 10 µM MK2206 or 10 µM H-89 for 30 minutes. (B) Western blot analysis of PRAS40 phosphorylation in ACLY WT cells upon treatment with 10 µM MK2206 or 10 µM H-89 for 30 minutes. (C) Western blot analysis of CREB phosphorylation upon treatment with 10 µM H-89 or 50 µM forskolin for 30 minutes (D) mRNA expression of IL6, CCL2 and CCL4 in ACLY WT and S455A THP-1 cells following treatment with 10 µM MK2206 or 10 µM H-89 for 30 minutes and 100 ng/ml LPS for 3 hours. (E) Western blot analysis of histone H3 acetylation at K9, K27, K14 and K23 in ACLY WT and S455A cells after treatment with 10 µM MK2206 or 10 µM H-89 for 30 minutes. Data represent mean values ± SE of 3-7 independent experiments. * p<0.05, ** p<0.01, *** p<0.001.
The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.
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Keywords: ATP-citrate lyase, histone acetylation, macrophages, metabolism, inflammation
Citation: Dominguez M, Truemper V, Mota AC, Brüne B and Namgaladze D (2024) Corrigendum: Impact of ATP-citrate lyase catalytic activity and serine 455 phosphorylation on histone acetylation and inflammatory responses in human monocytic THP-1 cells. Front. Immunol. 15:1434272. doi: 10.3389/fimmu.2024.1434272
Received: 17 May 2024; Accepted: 01 July 2024;
Published: 10 July 2024.
Edited and Reviewed by:
Francesca Granucci, University of Milano-Bicocca, ItalyCopyright © 2024 Dominguez, Truemper, Mota, Brüne and Namgaladze. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Dmitry Namgaladze, namgaladze@biochem.uni-frankfurt.de