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REVIEW article

Front. Immunol.
Sec. Cancer Immunity and Immunotherapy
Volume 15 - 2024 | doi: 10.3389/fimmu.2024.1433315

Immunotherapy for Colorectal Cancer

Provisionally accepted
Bing Yu Bing Yu 1*Jian Kang Jian Kang 1*Hong Lei Hong Lei 1*Zhe Li Zhe Li 1*Hao Yang Hao Yang 1,2Meng Zhang Meng Zhang 1*
  • 1 Department of the Colorectal Anal Surgery, the Affiliated Taian City Centeral Hospital of Qingdao University, Shandong Province, Taian, China
  • 2 Fifth Medical Center of the PLA General Hospital, Beijing, China

The final, formatted version of the article will be published soon.

    Colorectal cancer is the third most common cancer and the second most lethal cancer in the world.The main cause of the disease is due to dietary and behavioral factors. The treatment of this complex disease is mainly based on traditional treatments, including surgery, radiotherapy, and chemotherapy.Due to the high prevalence and high morbidity, more effective treatments with fewer side effects are urgently needed. In recent years, immunotherapy has become a potential therapeutic alternative and has become one of the fastest developing treatments. Immunotherapy inhibits tumor growth by activating or enhancing the immune system to recognize and attack cancer cells. This review presents the latest immunotherapies for immune checkpoint inhibitors, cell therapy, tumor-infiltrating lymphocytes, and oncolytic viruses. Some of these have shown promising results in clinical trials and used in clinical treatment.

    Keywords: colorectal cancer, Immunotherapy, immune checkpoint inhibitors, adoptive cell therapy, oncolytic virus

    Received: 16 May 2024; Accepted: 30 Jul 2024.

    Copyright: © 2024 Yu, Kang, Lei, Li, Yang and Zhang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Bing Yu, Department of the Colorectal Anal Surgery, the Affiliated Taian City Centeral Hospital of Qingdao University, Shandong Province, Taian, China
    Jian Kang, Department of the Colorectal Anal Surgery, the Affiliated Taian City Centeral Hospital of Qingdao University, Shandong Province, Taian, China
    Hong Lei, Department of the Colorectal Anal Surgery, the Affiliated Taian City Centeral Hospital of Qingdao University, Shandong Province, Taian, China
    Zhe Li, Department of the Colorectal Anal Surgery, the Affiliated Taian City Centeral Hospital of Qingdao University, Shandong Province, Taian, China
    Meng Zhang, Department of the Colorectal Anal Surgery, the Affiliated Taian City Centeral Hospital of Qingdao University, Shandong Province, Taian, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.