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CASE REPORT article

Front. Immunol.
Sec. Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders
Volume 15 - 2024 | doi: 10.3389/fimmu.2024.1432360
This article is part of the Research Topic Case Reports in Autoimmune and Autoinflammatory Disorders View all 36 articles

Breaking CNS immuno-privilege: TNFα-inhibitor triggers aseptic meningitis in a patient with Rheumatoid Arthritis

Provisionally accepted
Benedetta Kassabian Benedetta Kassabian 1Monica Facco Monica Facco 2Alessandro Miscioscia Alessandro Miscioscia 1Samuela Carraro Samuela Carraro 2Francesca Rinaldi Francesca Rinaldi 3Paolo Gallo Paolo Gallo 1Marco Puthenparampil Marco Puthenparampil 1*
  • 1 Department of Neuroscience, School of Medicine and Surgery, University of Padua, Padua, Italy
  • 2 Laboratory of Hematology and Immunology, Department of Medicine, School of Medicine and Surgery, University of Padua, Padova, Italy
  • 3 Neurological Clinic, University Hospital of Padua, Padua, Italy

The final, formatted version of the article will be published soon.

    Disclosures: Benedetta Kassabian has nothing to disclose. A. Miscioscia received travel grant from Novartis, Sanofi-Genzyme, and Biogen. Samuela Carraro and Monica Facco have nothing to disclose. Puthenparampil Marco received travel grant from Novartis, Genzyme, Biogen, Teva, Almirall and Sanofi-Genzyme; he has been consultant for Sanofi-Genzyme, Novartis., Biogen. Rinaldi Francesca serves as an advisory board member of Biogen-Idec and has received funding for travel and speaker honoraria from Merck Serono, Biogen Idec, Sanofi-Aventis, Teva and Bayer Schering Pharma. Paolo Gallo reports grants and personal fees from Novartis, grants and personal fees from Almirall, grants and personal fees from Biogen Idec, grants and personal fees from Sanofi Genzyme, grants and personal fees from Teva, grants and personal fees from Merck Serono, grants from University of Padova, grants from Italian Ministry of Public Health, grants from Veneto Region of Italy, grants from Italian Association for Multiple Sclerosis, outside the submitted work.

    Keywords: Rheumatoid arteritis, etanercept, Aseptic meningitis, Blood-Brain Barrier, Cerebrospinal Fluid, PET-MRI

    Received: 13 May 2024; Accepted: 25 Jul 2024.

    Copyright: © 2024 Kassabian, Facco, Miscioscia, Carraro, Rinaldi, Gallo and Puthenparampil. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Marco Puthenparampil, Department of Neuroscience, School of Medicine and Surgery, University of Padua, Padua, Italy

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