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REVIEW article

Front. Immunol.
Sec. Cancer Immunity and Immunotherapy
Volume 15 - 2024 | doi: 10.3389/fimmu.2024.1429483
This article is part of the Research Topic Overcoming Resistance of Immune Checkpoint Inhibitors View all articles

Traditional Chinese medicine and its components effectively reduce resistance mediated by immune checkpoint inhibitors

Provisionally accepted
Mingxin Guo Mingxin Guo 1Wentong Fang Wentong Fang 2Zhiqiang Hu Zhiqiang Hu 1*
  • 1 Yixing People's Hospital, Yixing, China
  • 2 Jiangsu province hospital, nanjing, China

The final, formatted version of the article will be published soon.

    Immunotherapy has become a global focus in cancer treatment and research, with promising results from targeting immune checkpoints in tumors like non-small cell lung cancer, colon cancer, and melanoma. However, resistance to immune checkpoint inhibitors (ICIs) remains a significant challenge. Traditional Chinese medicine (TCM), known for its low toxicity and minimal side effects, shows promise in enhancing cancer treatment when combined with modern therapies. This study reviews recent research on ICIs resistance mechanisms and highlights TCM's potential in overcoming this resistance, aiming to improve ICIs efficacy while minimizing toxicity.

    Keywords: Tumor immunotherapy, immune checkpoint inhibitors, Drug Resistance, Traditional Chinese Medicine, Chinese herb

    Received: 08 May 2024; Accepted: 06 Nov 2024.

    Copyright: © 2024 Guo, Fang and Hu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Zhiqiang Hu, Yixing People's Hospital, Yixing, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.