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CASE REPORT article

Front. Immunol.
Sec. Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders
Volume 15 - 2024 | doi: 10.3389/fimmu.2024.1425988

A case report and review of Rheumatoid arthritis co-occurring with tuberous sclerosis complex, a rare occurrence

Provisionally accepted
HaiQin Yin HaiQin Yin *Xuefei Li Xuefei Li Yao Fu Yao Fu Hui-Ling Zhu Hui-Ling Zhu
  • Jiujiang University Affiliated Hospital, Jiujiang, China

The final, formatted version of the article will be published soon.

    Rheumatoid arthritis (RA) is a common autoimmune disease. Tuberous sclerosis complex(TSC) is a rare autosomal dominant disorder. We report a case of RA with TSC. The patient was a 46-year-old woman with polyarthritis and cough symptoms, rheumatoid arthritis associated interstitial lung disease (RA-ILD) was initially considered, and after more than 3 months of anti-rheumatic treatment, the patient still had cough, and further examination revealed that the patient had lymphangioleiomyomatosis in the lungs, hepatic and renal angiomyolipomas, multiple subependymal nodules, Vertebral osteosclerotic nodules, as well as facial angiofibromas and periungual fibroma, RA was finally diagnosed with TSC, and everolimus 10mg qd was added to anti-rheumatic therapy for 1 month, and the patient's cough symptoms were relieved.

    Keywords: Pulmonary lymphangioleiomyomatosis, Angiomyolipoma, Periungual fibroma, Rheumatoid arthritis, Tuberous Sclerosis

    Received: 30 Apr 2024; Accepted: 03 Sep 2024.

    Copyright: © 2024 Yin, Li, Fu and Zhu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: HaiQin Yin, Jiujiang University Affiliated Hospital, Jiujiang, China

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