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REVIEW article

Front. Immunol.
Sec. T Cell Biology
Volume 15 - 2024 | doi: 10.3389/fimmu.2024.1408415
This article is part of the Research Topic Specific Targeting of MHC Antigens for T-cells and Immune Cells in Human Disease View all 5 articles

Composition, Functions, and Applications of Exosomal Membrane Proteins

Provisionally accepted
Fang Xu Fang Xu 1Shumin Luo Shumin Luo 1Pengpeng Lu Pengpeng Lu 1Chuanyun Li Chuanyun Li 1*Chao Cai Chao Cai 2*Weihua Li Weihua Li 2*
  • 1 Beijing Youan Hospital, Capital Medical University, Beijing, China
  • 2 Integrated Chinese and Western Medicine Center, Beijing Youan Hospital, Capital Medical University, Beijing, China

The final, formatted version of the article will be published soon.

    Exosomes play a crucial role in various biological processes, such as human development, immune responses, and disease occurrence.The membrane proteins on exosomes are pivotal factors for their biological functionality. Currently, numerous membrane proteins have been identified on exosome membranes, participating in intercellular communication, mediating target cell recognition, and regulating immune processes. Furthermore, membrane proteins from exosomes derived from cancer cells can serve as relevant biomarkers for early cancer diagnosis. This article provides a comprehensive review of the composition of exosome membrane proteins and their diverse functions in the organism's biological processes.Through in-depth exploration of exosome membrane proteins, it is expected to offer essential foundations for the future development of novel biomedical diagnostics and therapies.

    Keywords: Exosomes, Membrane Proteins, Functions, applications, Immunoregulation

    Received: 28 Mar 2024; Accepted: 15 Jul 2024.

    Copyright: © 2024 Xu, Luo, Lu, Li, Cai and Li. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Chuanyun Li, Beijing Youan Hospital, Capital Medical University, Beijing, China
    Chao Cai, Integrated Chinese and Western Medicine Center, Beijing Youan Hospital, Capital Medical University, Beijing, 100069, China
    Weihua Li, Integrated Chinese and Western Medicine Center, Beijing Youan Hospital, Capital Medical University, Beijing, 100069, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.