AUTHOR=Wang Li , Huang Shenyi , Liang Xiaolun , Zhou Junliang , Han Yifan , He Jiangshan , Xu Danping TITLE=Immuno-modulatory role of baicalin in atherosclerosis prevention and treatment: current scenario and future directions JOURNAL=Frontiers in Immunology VOLUME=15 YEAR=2024 URL=https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2024.1377470 DOI=10.3389/fimmu.2024.1377470 ISSN=1664-3224 ABSTRACT=
Atherosclerosis (AS) is recognized as a chronic inflammatory condition characterized by the accumulation of lipids and inflammatory cells within the damaged walls of arterial vessels. It is a significant independent risk factor for ischemic cardiovascular disease, ischemic stroke, and peripheral arterial disease. Despite the availability of current treatments such as statins, proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors, and lifestyle modifications for prevention, AS remains a leading cause of morbidity and economic burden worldwide. Thus, there is a pressing need for the development of new supplementary and alternative therapies or medications. Huangqin (