AUTHOR=Wang He , Shi Peng , Shi Xinyu , Lv Yaqing , Xie Hongwei , Zhao Hai TITLE=Surprising magic of CD24 beyond cancer JOURNAL=Frontiers in Immunology VOLUME=14 YEAR=2024 URL=https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2023.1334922 DOI=10.3389/fimmu.2023.1334922 ISSN=1664-3224 ABSTRACT=

CD24 has emerged as a molecule of significant interest beyond the oncological arena. Recent studies have unveiled its surprising and diverse roles in various biological processes and diseases. This review encapsulates the expanding spectrum of CD24 functions, delving into its involvement in immune regulation, cancer immune microenvironment, and its potential as a therapeutic target in autoimmune diseases and beyond. The ‘magic’ of CD24, once solely attributed to cancer, now inspires a new paradigm in understanding its multifunctionality in human health and disease, offering exciting prospects for medical advancements.