AUTHOR=Lahita Robert G. TITLE=Sex and gender influence on immunity and autoimmunity JOURNAL=Frontiers in Immunology VOLUME=14 YEAR=2023 URL=https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2023.1142723 DOI=10.3389/fimmu.2023.1142723 ISSN=1664-3224 ABSTRACT=
Autoimmune diseases are skewed toward one biological sex or another. This is the obvious observation of many decades, and it remains unexplained. Females predominate with most autoimmune diseases. The reasons for this predilection are an interplay of genetic, epigenetic and hormonal factors.