AUTHOR=Shen Jie , Zhang Mengyu , Zhang Ke , Qin Yahan , Liu Meifang , Liang Shujuan , Chen Daquan , Peng Meiyu TITLE=Effect of Angelica polysaccharide on mouse myeloid-derived suppressor cells JOURNAL=Frontiers in Immunology VOLUME=13 YEAR=2022 URL=https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2022.989230 DOI=10.3389/fimmu.2022.989230 ISSN=1664-3224 ABSTRACT=
Angelica polysaccharide (APS) is a polysaccharide extracted from Angelica sinensis and it is one of the main active components of Angelica sinensis. Many studies have demonstrated that APS can promote the activation and function of a variety of immune cells and is recognized as an immune enhancer, but the regulatory effect of APS on myeloid-derived suppressor cells (MDSC) is still unclear. In this study, we investigated the effects of APS on MDSC proliferation, differentiation and function through