AUTHOR=Wang Lu , Xu Haojie , Yang Huaxia , Zhou Jiaxin , Zhao Lidan , Zhang Fengchun TITLE=Glucose metabolism and glycosylation link the gut microbiota to autoimmune diseases JOURNAL=Frontiers in Immunology VOLUME=13 YEAR=2022 URL=https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2022.952398 DOI=10.3389/fimmu.2022.952398 ISSN=1664-3224 ABSTRACT=
Carbohydrates serve as important energy sources and structural substances for human body as well as for gut microbes. As evidenced by the advances in immunometabolism, glucose metabolism and adenosine triphosphate (ATP) generation are deeply involved in immune cell activation, proliferation, and signaling transduction as well as trafficking and effector functions, thus contributing to immune response programming and assisting in host adaption to microenvironment changes. Increased glucose uptake, aberrant expression of glucose transporter 1 (