AUTHOR=Wang Sheng , Zhang Liyun , Hao Dongsheng , Wang Lei , Liu Jiaxi , Niu Qing , Mi Liangyu , Peng Xinyue , Gao Jinfang 

TITLE=Research progress of risk factors and early diagnostic biomarkers of gout-induced renal injury

JOURNAL=Frontiers in Immunology

VOLUME=13

YEAR=2022

URL=https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2022.908517

DOI=10.3389/fimmu.2022.908517

ISSN=1664-3224

ABSTRACT=<p>Gout renal injury has an insidious onset, no obvious symptoms, and laboratory abnormalities in the early stages of the disease. The injury is not easily detected, and in many cases, the patients have entered the renal failure stage at the time of diagnosis. Therefore, the detection of gout renal injury–related risk factors and early diagnostic biomarkers of gout renal injury is essential for the prevention and early diagnosis of the disease. This article reviews the research progress in risk factors and early diagnostic biomarkers of gout renal injury.</p>