AUTHOR=Tang Shuang , Li Jie , Chang Yung-Fu , Lin Wencheng TITLE=Avian Leucosis Virus-Host Interaction: The Involvement of Host Factors in Viral Replication JOURNAL=Frontiers in Immunology VOLUME=13 YEAR=2022 URL=https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2022.907287 DOI=10.3389/fimmu.2022.907287 ISSN=1664-3224 ABSTRACT=

Avian leukosis virus (ALV) causes various diseases associated with tumor formation and decreased fertility. Moreover, ALV induces severe immunosuppression, increasing susceptibility to other microbial infections and the risk of failure in subsequent vaccination against other diseases. There is growing evidence showing the interaction between ALV and the host. In this review, we will survey the present knowledge of the involvement of host factors in the important molecular events during ALV infection and discuss the futuristic perspectives from this angle.