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ADDENDUM article

Front. Immunol., 11 March 2022
Sec. Inflammation

Addendum: Increased Circulating T Follicular Helper Cells Induced via IL-12/21 in Patients With Acute on Chronic Hepatitis B Liver Failure

  • 1Department of Infectious Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
  • 2Department of Infectious Diseases, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
  • 3Department of Hematology, Children Hospital, Soochow University, Suzhou, China
  • 4Clinical Research Centre, The Affiliated Changshu Hospital of Xuzhou Medical University, Changshu, China

An Addendum on
Increased Circulating T Follicular Helper Cells Induced via IL-12/21 in Patients With Acute on Chronic Hepatitis B Liver Failure

By Du B, Teng J, Yin R, Tian Y, Jiang T, Du Y and Cai W (2021). Front. Immunol. 12:641362. doi: 10.3389/fimmu.2021.641362

In response to comments on PubPeer, the author uploaded the raw data as Supplementary Material 2 to support Figures 4A–C in the original file. The authors apologize to the readership for any inconvenience caused.

These experiments were completed from July to September 2012. The workspace can’t be used due to the upgrade of the version of FlowJo. The data were reanalyzed using the same gating and labelling in FlowJo version 10.6. The results are presented in the format of Pseudocolour. The trend of the data has not changed, which does not affect the original results.

The authors uploaded the FCS format raw data and Pseudocolour format graphical of all 6 patients, which mentioned in the original article (n=6, and original figure 4 shows the flow analysis data of patient #1).

The documents are as follows:

1) Data 1: FACS raw files of patient (n=6. A patient’s data is summarized in a folder. Each folder contains 23 FCS files, which are marked according to the processing.)

2) Data:2: Figure panels of Pseudocolour format graphical (n=6. One page per patient) in PPT.

Publisher’s Note

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.

Supplementary Material

The Supplementary Material for this article can be found online at: https://www.frontiersin.org/articles/10.3389/fimmu.2022.798058/full#supplementary-material

Keywords: T follicular helper cell, hepatitis B virus-related acute on chronic liver failure, pathogenesis, interleukin-21, interleukin-12

Citation: Du B, Teng J, Yin R, Tian Y, Jiang T, Du Y and Cai W (2022) Addendum: Increased Circulating T Follicular Helper Cells Induced via IL-12/21 in Patients With Acute on Chronic Hepatitis B Liver Failure. Front. Immunol. 13:798058. doi: 10.3389/fimmu.2022.798058

Received: 19 October 2021; Accepted: 22 February 2022;
Published: 11 March 2022.

Edited and reviewed by:

Navin Kumar Verma, Nanyang Technological University, Singapore

Copyright © 2022 Du, Teng, Yin, Tian, Jiang, Du and Cai. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

*Correspondence: Wei Cai, carieyc@hotmail.com; Yanan Du, xiaodunn@126.com; Tingwang Jiang, jtwgyp@163.com

These authors have contributed equally to this work and share first authorship

These authors have contributed equally to this work and share last authorship

Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.