AUTHOR=Fernández-Fournier Mireya , Lacruz Laura , Nozal Pilar , Chico Juan Luis , Tallón Barranco Antonio , Otero-Ortega Laura , Corral Iñigo , Carrasco Angela 

TITLE=The study of neural antibodies in neurology: A practical summary

JOURNAL=Frontiers in Immunology

VOLUME=13

YEAR=2022

URL=https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2022.1043723

DOI=10.3389/fimmu.2022.1043723

ISSN=1664-3224

ABSTRACT=<p>The field of Autoimmune Neurology is expanding rapidly, with new neural antibodies being identified each year. However, these disorders remain rare. Deciding when to test for these antibodies, when and what samples are to be obtained, how to handle and study them correctly, and how to interpret test results, is complex. In this article we review current diagnostic techniques and provide a comprehensive explanation on the study of these patients, in an effort to help with correct diagnosis minimizing false positive and false negative results. We also propose routine storage of samples and referral of certain cases to specialized research laboratories.</p>