AUTHOR=Keitel Verena , Bode Johannes Georg , Feldt Torsten , Walker Andreas , Müller Lisa , Kunstein Anselm , Klindt Caroline , Killer Alexander , Senff Tina , Timm Jörg , Ostermann Philipp , Damagnez Maximilian , Lübke Nadine , Adams Ortwin , Schaal Heiner , Antoch Gerald , Neubert Jennifer , Albrecht Philipp , Meuth Sven , Elben Saskia , Mohring Annemarie , Fischer Johannes C. , Bölke Edwin , Hoenig Manfred , Schulz Ansgar S. , Luedde Tom , Jensen Björn 

TITLE=Case Report: Convalescent Plasma Achieves SARS-CoV-2 Viral Clearance in a Patient With Persistently High Viral Replication Over 8 Weeks Due to Severe Combined Immunodeficiency (SCID) and Graft Failure

JOURNAL=Frontiers in Immunology

VOLUME=12

YEAR=2021

URL=https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2021.645989

DOI=10.3389/fimmu.2021.645989

ISSN=1664-3224

ABSTRACT=<p>We describe the unique disease course and cure of SARS-CoV-2 infection in a patient with SCID and graft failure. In absence of a humoral immune response, viral clearance was only achieved after transfusion of convalescent plasma. This observation underscores the necessity of the humoral immune response for SARS-CoV-2 clearance.</p>