AUTHOR=Gojkovic Milos , Cunha Pedro P. , Darmasaputra Gabriella S. , Barbieri Laura , Rundqvist Helene , Veliça Pedro , Johnson Randall S. TITLE=Oxygen-Mediated Suppression of CD8+ T Cell Proliferation by Macrophages: Role of Pharmacological Inhibitors of HIF Degradation JOURNAL=Frontiers in Immunology VOLUME=Volume 12 - 2021 YEAR=2021 URL=https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2021.633586 DOI=10.3389/fimmu.2021.633586 ISSN=1664-3224 ABSTRACT=
Myeloid cell interactions with cells of the adaptive immune system are an essential aspect of immunity. A key aspect of that interrelationship is its modulation by the microenvironment. Oxygen is known to influence myelosuppression of T cell activation in part