AUTHOR=Song Wenpeng , Ye Jing , Pan Nanfang , Tan Chunyu , Herrmann Martin TITLE=Neutrophil Extracellular Traps Tied to Rheumatoid Arthritis: Points to Ponder JOURNAL=Frontiers in Immunology VOLUME=11 YEAR=2021 URL=https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2020.578129 DOI=10.3389/fimmu.2020.578129 ISSN=1664-3224 ABSTRACT=

In recent years, neutrophil extracellular traps at the forefront of neutrophil biology have proven to help capture and kill pathogens involved in the inflammatory process. There is growing evidence that persistent neutrophil extracellular traps drive the pathogenesis of autoimmune diseases. In this paper, we summarize the potential of neutrophil extracellular traps to drive the pathogenesis of rheumatoid arthritis and experimental animal models. We also describe the diagnosis and treatment of rheumatoid arthritis in association with neutrophil extracellular traps.