AUTHOR=Zhou Xu , Sun Lihua , Yao Xiaoxiao , Li Guangquan , Wang Yicun , Lin Yang 

TITLE=Progress in Vaccination of Prophylactic Human Papillomavirus Vaccine

JOURNAL=Frontiers in Immunology

VOLUME=11

YEAR=2020

URL=https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2020.01434

DOI=10.3389/fimmu.2020.01434

ISSN=1664-3224

ABSTRACT=<p>The human papillomavirus (HPV) vaccine plays an important role in preventing a series of diseases caused by HPV. Recent studies have shown that as a primary prevention measure, it can considerably prevent HPV infection and HPV-associated cervical cancer. However, studies on the safety, efficacy, and coverage of the HPV vaccine remain insufficient, especially in developing countries. Therefore, in this review, we outlined the recent studies of the HPV vaccine in terms of immunogenicity, safety, efficacy, latest vaccination concepts, and strategies. This review may provide a theoretical basis for use of the HPV vaccine.</p>