AUTHOR=Wang Yijie , Zhang John H. , Sheng Jifang , Shao Anwen 

TITLE=Immunoreactive Cells After Cerebral Ischemia

JOURNAL=Frontiers in Immunology

VOLUME=10

YEAR=2019

URL=https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2019.02781

DOI=10.3389/fimmu.2019.02781

ISSN=1664-3224

ABSTRACT=<p>The immune system is rapidly activated after ischemic stroke. As immune cells migrate and infiltrate across the blood-brain barrier into the ischemic region, a cascade of cellular and molecular biological reactions occur, involving migrated immune cells, resident glial cells, and the vascular endothelium. These events regulate infarction evolution and thus influence the outcome of ischemic stroke. Most immune cells exert dual effects on cerebral ischemia, and some crucial cells may become central targets in ischemic stroke treatment and rehabilitation.</p>