AUTHOR=ten Brinke Anja , Martinez-Llordella Marc , Cools Nathalie , Hilkens Catharien M. U. , van Ham S. Marieke , Sawitzki Birgit , Geissler Edward K. , Lombardi Giovanna , Trzonkowski Piotr , Martinez-Caceres Eva 

TITLE=Ways Forward for Tolerance-Inducing Cellular Therapies- an AFACTT Perspective

JOURNAL=Frontiers in Immunology

VOLUME=10

YEAR=2019

URL=https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2019.00181

DOI=10.3389/fimmu.2019.00181

ISSN=1664-3224

ABSTRACT=<p>Clinical studies with cellular therapies using tolerance-inducing cells, such as tolerogenic antigen-presenting cells (tolAPC) and regulatory T cells (Treg) for the prevention of transplant rejection and the treatment of autoimmune diseases have been expanding the last decade. In this perspective, we will summarize the current perspectives of the clinical application of both tolAPC and Treg, and will address future directions and the importance of immunomonitoring in clinical studies that will result in progress in the field.</p>