AUTHOR=Kanmani Paulraj , Albarracin Leonardo , Kobayashi Hisakazu , Hebert Elvira Maria , Saavedra Lucila , Komatsu Ryoya , Gatica Brian , Miyazaki Ayako , Ikeda-Ohtsubo Wakako , Suda Yoshihito , Aso Hisashi , Egusa Shintaro , Mishima Takashi , Salas-Burgos Alexis , Takahashi Hideki , Villena Julio , Kitazawa Haruki TITLE=Genomic Characterization of Lactobacillus delbrueckii TUA4408L and Evaluation of the Antiviral Activities of its Extracellular Polysaccharides in Porcine Intestinal Epithelial Cells JOURNAL=Frontiers in Immunology VOLUME=9 YEAR=2018 URL=https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2018.02178 DOI=10.3389/fimmu.2018.02178 ISSN=1664-3224 ABSTRACT=
In lactic acid bacteria, the synthesis of exopolysaccharides (EPS) has been associated with some favorable technological properties as well as health-promoting benefits. Research works have shown the potential of EPS produced by lactobacilli to differentially modulate immune responses. However, most studies were performed in immune cells and few works have concentrated in the immunomodulatory activities of EPS in non-immune cells such as intestinal epithelial cells. In addition, the cellular and molecular mechanisms involved in the immunoregulatory effects of EPS have not been studied in detail. In this work, we have performed a genomic characterization of