Skip to main content

SYSTEMATIC REVIEW article

Front. Hum. Neurosci.

Sec. Motor Neuroscience

Volume 19 - 2025 | doi: 10.3389/fnhum.2025.1549379

Effect of robot-assisted training for lower limb rehabilitation on lower limb function in stroke patients: a systematic review and meta-analysis

Provisionally accepted
Hongyao Wang Hongyao Wang Haifei Shen Haifei Shen *Junjie Wang Junjie Wang *Yi Han Yi Han *Wenlu Zhou Wenlu Zhou *
  • Zhejiang Chinese Medical University, Hangzhou, China

The final, formatted version of the article will be published soon.

    Objective: The effectiveness of lower extremity rehabilitation robots in rehabilitating stroke patients is still controversial. With this systematic review, the aim is to analyze whether the assisted training of the lower limb rehabilitation robot is more effective in promoting the rehabilitation of lower limb function in stroke patients compared with traditional physical therapy.We conducted a thorough search of nine databases for relevant randomized controlled trials published between the time of their construction and February 2024. The Cochrane Collaboration tool was used to assess the risk of bias in each included literature, and meta-analyses and subgroup analyses were carried out with Revman 5.4 software. This study followed the PRIMA reporting statement provided by EQUATOR.The meta-analysis includes 12 articles and 651 patients. Lower limb rehabilitation robot-assisted training significantly improved lower limb motor function, walking ability, and lower limb ability to balance in stroke patients. However, the effect on gait coordination was not statistically significant.Robot-assisted training for lower limb rehabilitation may considerably enhance motor function, walking capacity, and balance function in stroke patients while also providing a novel option for patients to recuperate.

    Keywords: Robot-assisted, Stroke, Lower limb function, Rehabilitation, Meta-analysis, Systematic review

    Received: 21 Dec 2024; Accepted: 17 Feb 2025.

    Copyright: © 2025 Wang, Shen, Wang, Han and Zhou. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Haifei Shen, Zhejiang Chinese Medical University, Hangzhou, China
    Junjie Wang, Zhejiang Chinese Medical University, Hangzhou, China
    Yi Han, Zhejiang Chinese Medical University, Hangzhou, China
    Wenlu Zhou, Zhejiang Chinese Medical University, Hangzhou, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

    Research integrity at Frontiers

    Man ultramarathon runner in the mountains he trains at sunset

    94% of researchers rate our articles as excellent or good

    Learn more about the work of our research integrity team to safeguard the quality of each article we publish.


    Find out more