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ORIGINAL RESEARCH article

Front. Hum. Neurosci.
Sec. Brain Imaging and Stimulation
Volume 18 - 2024 | doi: 10.3389/fnhum.2024.1387212
This article is part of the Research Topic Neuroimaging and Connectivity Research in Latin America and the Caribbean View all articles

Morphological characterization of the hippocampus: a first database in Ecuador

Provisionally accepted
Stefano B. Cevallos Stefano B. Cevallos 1Alex X. Jerves Alex X. Jerves 1,2*Clayreth Vinueza Clayreth Vinueza 3,4Dennis Hernandez Dennis Hernandez 4Carlos Ávila Carlos Ávila 5Andrés Auquilla Andrés Auquilla 6Óscar Alvear Óscar Alvear 1
  • 1 Fundación INSPIRE, Quito, Ecuador
  • 2 Catholic University of Cuenca, Cuenca, Ecuador
  • 3 International University of Ecuador, Quito, Pichincha, Ecuador
  • 4 Medimagenes, Quito, Ecuador
  • 5 Equinox University of Technology, Quito, Pichincha, Ecuador
  • 6 University of Cuenca, Cuenca, Azuay, Ecuador

The final, formatted version of the article will be published soon.

    Introduction: the hippocampal volume is a well-known biomarker to detect and diagnose neurological, psychiatric, and psychological diseases. However, other morphological descriptors are not analyzed.Furthermore, not available databases, or studies, were found with information related to the hippocampal morphology from Latin-American patients living in the Andean highlands.Methods: the hippocampus is manually segmented by two medical imaging specialists on normal brain magnetic resonance images. Then, its morphological qualitative and quantitative descriptors (volume, sphericity, roundness, diameter, volume-surface ratio, and aspect ratio) are computed via 3D digital levelset-based mathematical representation. Furthermore, other morphological descriptors and their possible correlation with the hippocampal volume is analyzed.Results: we introduce a first database with the hippocampus' morphological characterization of 63 patients from Quito, Ecuador, male and female, aged between 18 and 95 years old.

    Keywords: Andean patients, database, Hippocampus, Level sets, MRI, Morphological parameters, volume

    Received: 17 Feb 2024; Accepted: 16 Sep 2024.

    Copyright: © 2024 Cevallos, Jerves, Vinueza, Hernandez, Ávila, Auquilla and Alvear. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Alex X. Jerves, Catholic University of Cuenca, Cuenca, Ecuador

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.